The following is the full text of the speech by Academician Chen Runsheng. Based on the actual record, the author did not change the original editor:
Dear experts and leaders, I am very honored to be able to attend this meeting. I think I’m talking about big data and precision medicine today, because now everyone knows that precision medicine is very hot, even though it is younger than artificial intelligence, but We know that on January 20, 2005, the United States President Barack Obama launched his research on precision medicine in the United States. Since then, precision medicine has received universal attention in the world. In many developed countries, including our country, we are not just everyone. In an area that we are all very concerned about, our national leaders have many important instructions for the development of precision medicine, and they also have concrete manifestations in funding. So today I mainly talk about the four aspects of precision medicine. One is to communicate with everyone and I also hope to have some discussions.
1. Accurate medicine is the combination of big data and clinical medicine
The first question is what is the essence of precision medicine and what is the core? I saw various kinds of comments in the country. There are various opinions about the meaning of precision medicine. I feel that the core of precision medicine is actually one point, very clear, that is, the combination of big data and medicine. More specifically, it is the combination of big data and clinical medicine. In other words, the big data of the group is used in clinical medicine to improve the accuracy of medical diagnosis and improve the effect of treatment.
Here, it also includes two layers of meaning. One meaning is big data for group studies, and the other is medicine. Then the big data of the group includes two meanings. One is the group science and the other is the big data. We know that in recent years, with the development of clinical research, we have gained more and more human information represented by the genome at the molecular level. This is unprecedented before. Then, with the development of histological data represented by the genome, more and more people have accumulated not only genetic information but also protein information represented by the genetic code. Later, people discovered and tapped these data. Information will later receive a lot of information that reflects human health and disease. Therefore, it has been suggested that if these information are applied to the clinic, the clinical effect will be improved. This is the essence of so-called precision medicine. However, it is not enough to only obtain information on these genetic codes.
We all know that all genetic code information is a very, very big piece of big data. This big data is very easy to measure. We now know that in our country, everyone can spend 10,000 yuan to get your genetics. Password, but you don't understand your genetic code because you only have four words (A, C, G, T), so to understand him, you need to develop theoretical methods and techniques for big data analysis. . Therefore, to use these group data in a large clinical context, it must be a combination of histological data and big data analysis methods. Therefore, one part is the big data of group science, and the other is medicine. The combination of the two forms the essence and core of precision medicine. This is the first problem. With regard to the essence of precision medicine, he was also used in the clinical research in the 1990s due to histological data. He has developed and transformed into translational medicine and individualized medicine. He now has the name of precision medicine from 2011, but anyway, It is his essence that is clear, that is, the application of big data in clinical medicine.
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